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E-mail: emily.read@qmul.ac.uk
I am interested in applying my background as a mucosal immunologist to characterise host–microbial interactions in understudied and threatened systems. My research aims to understand how host glycan (sugar chain) profiles present in the amphibian skin mucosa shape microbial community composition and colonisation of the devasting fungal pathogen Batrachochytrium dendrobatidis (Bd). This approach not only provides a fundamental insight into how host factors shape microbiome assembly at a key barrier site, but also has the potential to develop new strategies against Bd that support long-lasting conservation of threatened amphibian species.
Publications
Lo, J.W., Schroeder, J.H., Roberts, L.B., Mohamed, R., Cozzetto, D., Beattie, G., Omer, O.S., Ross, E.M., Heuts, F., Jowett, G.M. and Read, E. CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner. Nature Communications DOI:10.1038/s41467-024-51719-6 (2024)
*Read, E., Peña-Cearra, A., Coman, D., Jowett, G. M., ... & Neves, J. F. Bi-directional signaling between the intestinal epithelium and type-3 innate lymphoid cells regulates secretory dynamics and interleukin-22. Mucosal Immunology DOI:10.1016/j.mucimm.2023.11.002 (2024)
*Read, E., Jowett, G. M., Coman, D., & Neves, J. F. Co-culture of murine small intestine epithelial organoids with innate lymphoid cells. JoVE DOI:10.3791/63554 (2022)
Jowett, G. M., Read, E., Roberts, L. B., Coman, D., González, M. V., Zabinski, T., ... & Neves, J. F. Organoids capture tissue-specific innate lymphoid cell development in mice and humans. Cell Reports DOI:10.1016/j.celrep.2022.111281 (2022)
*Read, E., Curtis, M. A., & Neves, J. F. The role of oral bacteria in inflammatory bowel disease. Nature Reviews Gastroenterology & Hepatology DOI:10.1038/s41575-021-00488-4 (2021)
Jowett, G. M., Norman, M. D., Yu, T. T., Rosell Arevalo, P., Hoogland, D., Lust, S. T., Read, E., ... & Gentleman, E. ILC1 drive intestinal epithelial and matrix remodelling. Nature Materials DOI:10.1038/s41563-020-0783-8 (2021)
Roberts, L. B., Jowett, G. M., Read, E., Zabinski, T., Berkachy, R., Selkirk, M. E., ... & Lord, G. M. MicroRNA-142 critically regulates group 2 innate lymphoid cell homeostasis and function. The Journal of Immunology DOI:10.4049/JIMMUNOL.2000647 (2021)
Schoeder, J.H., Roberts, L.B., Meissl, K., Lo, J.W., Hromadová, D., Hayes, K., Zabinski, T., Read, E., ... & Lord, G. M. Sustained post-developmental T-bet expression is critical for the maintenance of type one innate lymphoid cells in vivo. Frontiers in Immunology DOI:10.3389/fimmu.2021.760198 (2021)
Bankole, E., Read, E., Curtis, M. A., Neves, J. F., & Garnett, J. A. The relationship between mucins and ulcerative colitis: a systematic review. Journal of Clinical Medicine DOI:10.3390/jcm10091935 (2021)
Clarke, G., Harley, P., Hubber, E. L., Manea, T., Manuelli, L., Read, E., & Watt, F. M. Bench to bedside: Current advances in regenerative medicine. Current Opinion in Cell Biology DOI:10.1016/j.ceb.2018.05.006 (2018)
Yu, S. C., Dawson, A., Henderson, A. C., Lockyer, E. J., Read, E., Sritharan, G., ... & Spanu, P. D. Nutrient supplements boost yeast transformation efficiency. Scientific Reports DOI:10.1038/srep35738 (2016)
Education
2022 PhD in Immunology, Wellcome Trust studentship, Cell Therapies and Regenerative Medicine Programme. King’s College London
2018 MRes in Biomedical and Translation Sciences, (Distinction). King’s College London
2017 BSc in Biological Sciences with a Year in Industry, (Hons) (1st) Imperial College London, London & GlaxoSmithKline, Stevenage
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